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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumors

Fig. 7

Association of monocyte proportion with PD-L1 and PD-L2 gene expression and gene promoter methylation (N = 594). a Scatterplot of Monocyte proportion against the gene expression of PD-L1 showed significant positive correlation. b Scatterplot of Monocyte proportion against the promoter methylation of PD-L1 showed significant negative correlation. c Bar plot of 594 sample arranged from high to low expression of PD-L1. Arranged samples showed probe methylation low to high (Opposite to gene expression) and monocyte proportion high to low, similar to gene expression. d Scatterplot of Monocyte proportion against the gene expression of PD-L2 showed significant positive correlation. e Scatterplot of Monocyte proportion against the promoter methylation of PD-L2 showed significant negative correlation as compared to PD-L1. f Bar plot of 594 sample arranged from high to low expression of PD-L2. Arranged samples showed probe methylation low to high (Opposite to gene expression) and monocyte proportion high to low, similar to gene expression

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