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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumors

Fig. 1

Signature matrix generation a t-SNE plot showing distinct clusters of methylation profiles of the pure reference cell types used to generate signature matrix. b Heatmap generated by all selected probes of signature matrix. c Scatterplot showing the estimated CIBERSORT cancer fraction (N = 4052) correlates significantly with purity (Estimate purity; R = 0.59; p value < 2.2 × 10–16, Absolute purity; R = 0.76; p value < 2.2 × 10–16)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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