Fig. 4
From: Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS
Gray matter hemoglobin leakage along the spinal cord axis. Immunohistochemical labelling (a) and automated analysis outputs (b) of extravascular hemoglobin in control and ALS spinal cord gray matter. Scale bars = 1 mm. Quantification of extravascular hemoglobin in gray matter at individual segmental levels C8, T7–T9 and L4/L5 in control (c) and ALS (d) cases. Data shown as mean ± SD (control n = 4, ALS n = 13), with statistical significance determined using two-way ANOVA with Tukey’s post-test. ns, not significant