Fig. 8

IHC staining of the substantia nigra in ethanol fixed tissue sections from an LBD patient with antibodies to full-length or carboxy truncated forms of αSyn. Substantia nigra tissue sections were labeled with antibody 94-3A10 that reacts with amino acid region 130–140 in αSyn and antibodies (2B1, 5C1, 10A4, 4H11, and 2G5) specific for carboxy truncated forms of αSyn strongly labeled classic LBs. Tissue sections were stained with the αSyn antibodies indicated in the top left corner. All sections were counterstained with hematoxylin. Scale bar = 50 μm