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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery

Fig. 4

Gene ontology and molecular pathway analyses of transcriptomic changes in recovery-phase microglia. A Statistical significance of overrepresented gene ontology annotations (biological pathway subcategory) among genes showing significantly higher expression (log2 fold change > 1, Benjamini–Hochberg adjusted P-value < 0.05) in recovery-phase relative to control microglia in the cortex (left panel) or spinal cord (right panel). B Statistical significance of overrepresented Reactome pathway annotations among genes showing significantly higher expression (log2 fold change > 1, Benjamini–Hochberg adjusted P-value < 0.05) in recovery-phase relative to control microglia in the cortex (left panel) or spinal cord (right panel)

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