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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions

Fig. 3

Imaging and histopathological features of Case #11. a–f Left occipital cortical cystic mass with tissular mural nodule. a Tissular part is slightly hyperdense on CT. b peritumoral edema and hyperintense cystic content on T2-weighted sequence. c Cyst content isointense on FLAIR image. d Intense contrast enhancement on T1-weighted sequence after gadolinium injection. e Diffusion restriction. f Intermediate tumoral blood flow on Arterial Spin Labelling perfusion imaging. g Sarcoma-like pattern composed of fascicles of spindle cells (HPS, magnification × 100). h Tumor composed of spindle cells (HPS, magnification × 400). i Tumor with a dense reticulin network (magnification × 400). j The tumor cells did not express GFAP (magnification × 400). k A dot-like and cytoplasmic pattern of staining for EMA in the tumor (magnification × 400). l Diffuse staining for L1CAM (magnification × 400). Black scale bars represent 250 μm (g) and 50 µm (hl). CT: computerized tomodensitometry; HPS: Hematoxylin Phloxin Saffron

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