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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions

Fig. 2

Imaging and histopathological features of Case #3. a–c Right frontotemporal cystic mass with thick walls. a Cyst fluid–fluid level on T2-weighted sequence. b Intense contrast enhancement of the tissular part on T1-weighted sequence after gadolinium injection. c Diffusion restriction. d Astroblastoma-like pattern composed of multiple pseudorosettes (HPS, magnification × 100). e Pseudorosettes composed of a central vessel and variable sclerosis (HPS, magnification × 200). f Perivascular pseudorosettes composed of elongated cells containing an abundant eosinophilic cytoplasm (HPS, magnification × 200). g The tumor cells strongly expressed GFAP (magnification × 400). h A dot-like and apical pattern of staining for EMA in the tumor (magnification × 400). i Diffuse staining for L1CAM (magnification × 400). Black scale bars represent 250 μm (d), 100 µm (e) and 50 µm (fi). HPS: Hematoxylin Phloxin Saffron

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