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Table 1 Human participant demographics

From: Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice

 

NCI (No cognitive impairment)

MCI (Mild cognitive impairment)

AD (Alzheimer’s dementia)

# Samples

20

20

20

Age at death (yr)

87.16 ± 3.39

87.42 ± 3.32

87.38 ± 3.58

Male/female

4/16

4/16

4/16

Education (yr)

17.60 ± 1.39

17.60 ± 1.39

17.70 ± 1.49

Post-mortem interval (hr)

6.21 ± 3.96

9.31 ± 5.40

6.97 ± 4.29

Total amyloid-β (% area)

4.27 ± 3.76

1.90 ± 1.80

3.92 ± 3.27

Tau tangle density

3.88 ± 0.55

3.61 ± 0.98

10.47 ± 10.74