Fig. 3

Correlation of number of pericytes per COL4 area and age in the frontal cortex. A, Scatter plot showing negative correlation between number of pericytes per COL4 area (mm²) and age amongst young control and older control (Control) subjects, suggesting ageing effects on pericytes numbers in the cerebral cortex (Pearson’s r =  − 0.73, P = 0.0003). B, Number of pericytes per COL4 area (mm²) and age in all dementias and control subjects were also negatively correlated (Pearson’s r =  − 0.28, P = 0.02), implicating pericytes tend to be reduced with ageing in the total sample indicating an ageing effect in disease groups