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Table 2 Partial Spearman correlations of semiquantitative MTL scores of neurodegenerative pathologies with MTL subregional thickness measures, including all pathologies in the same model

From: Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions

  ERC BA35 BA36 PHC SUB CA1 SRLM
Sample size 55 53 53 56 58 58 57
Amyloid-β 0.10 0.11  − 0.02  − 0.18 0.05 0.05 0.16
Tau  − 0.26a  − 0.31* 0.08 0.06  − 0.13  − 0.16  − 0.33*
TDP-43  − 0.44**  − 0.46**  − 0.35*  − 0.45***  − 0.27a  − 0.39**  − 0.46***
α-synuclein 0.01  − 0.01 0.02 0.12 0.16 0.17  − 0.12
  1. All models are corrected for age, sex and hemisphere
  2. ap < 0.10; *p < 0.05; **p < 0.01; ***p < 0.001. Significant results are bolded. TDP TAR DNA-binding protein, ERC entorhinal cortex, BA Brodmann area, PHC parahippocampal cortex, SUB subiculum, CA cornu ammonis, SRLM stratum radiatum lacunosum moleculare