Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer’s disease

Table 3 Case IHC data summary

Case #	Dx	pSRRM2	MSUT2	AT180
10	AD	Cytoplasmic	Depleted	+++
6	AD	Cytoplasmic	Depleted	+++
8	AD	Cytoplasmic	Depleted	+++
9	AD	Cytoplasmic	Depleted	+++
16	AD	Cytoplasmic	Positive	+++
5	AD	Cytoplasmic	Depleted	+++
1	AD	Cytoplasmic	Depleted	+++
2	AD	Cytoplasmic	Depleted	+++
3	AD	Cytoplasmic	Depleted	+++
7	AD	Cytoplasmic	Depleted	++
13	AD	Cytoplasmic	Positive	++
11	AD	Cytoplasmic	Depleted	++
4	AD	Cytoplasmic	Depleted	++
12	AD	Cytoplasmic	Positive	++
18	AD	Mixed	Depleted	+++
17	AD	Mixed	Depleted	+++
20	AD	Mixed	Positive	++
19	AD	Mixed	Depleted	+
28	AD	Nuclear	Positive	++
23	AD	Nuclear	Positive	++
29	AD	Nuclear	Positive	+
24	AD	Nuclear	Positive	+
22	AD	Nuclear	Positive	+
21	AD	Nuclear	Positive	+
26	AD	Nuclear	Positive	+
27	AD	Nuclear	Positive	+

ISSN: 2051-5960