Fig. 5
From: RBM5-AS1 promotes radioresistance in medulloblastoma through stabilization of SIRT6 protein
Ectopic expression of RBM5-AS1 confers radioresistance to medulloblastoma cells. A Quantitative real-time PCR analysis of RBM5-AS1 levels in both DAOY and D283Med cells transfected with empty vector or RBM5-AS1-expressing plasmid. B Detection of apoptosis in DAOY and D283Med cells transfected with empty vector or RBM5-AS1-expressing plasmid after irradation. C Assessment of DNA damage response in the cells treated as in B. D Clonogenic survival assay showing that RBM5-AS1-overexpressing cells were more resistant to radiation than control cells. *P < 0.05