Table 1 Patients’ and controls’ demographic features
From: Pathology of the neurovascular unit in leukodystrophies
Donor | Age at death (years) | Sex | Clinical diagnosis | Abbreviation | Primary cell type involved |
|---|---|---|---|---|---|
Patient 1 | 17 | F | Aicardi-Goutières syndrome | AGS | Astrocytes |
Patient 2 | 32 | M | Alexander disease, adolescent-onset | AxD | Astrocytes |
Patient 3 | 13 | F | Alexander disease, infantile-onset | AxD | Astrocytes |
Patient 4 | 75 | F | Cathepsin A-related arteriopathy with strokes and leukoencephalopathy | CARASAL | Blood vessels |
Patient 5 | 32 | F | Adult-onset leukodystrophy with spheroids and pigmented glia | ALSP | Microglia |
Patient 6 | 36 | F | LARS2-related leukodystrophy | Â | Astrocytes |
Patient 7 | 5 | F | Metachromatic leukodystrophy | MLD | Oligodendrocytes |
Patient 8 | 14 | M | Pelizaeus-Merzbacher disease | PMD | Oligodendrocytes |
Patient 9 | 70 | M | X-linked adrenoleukodystrophy | X-ALD | Oligodendrocytes |
Control 1 | 27 | M | Lymphocytic myocarditis | Â | Â |
Control 2 | 5 | F | Viral pneumonia | Â | Â |
Control 3 | 12 | M | Osteosarcoma | Â | Â |