Fig. 4
From: Pathology of the neurovascular unit in leukodystrophies
AQP4 expression in the frontal WM of non-neurological controls and leukodystrophy patients. In controls, AQP4 is only expressed at the perivascular astrocytic endfeet, as expected. In all assessed leukodystrophies, there is prominent redistribution of AQP4 to the plasma membrane of non-blood vessel related astrocytic cell processes. Astrocytes are stained with GFAP, endothelial cells with UEA I and nuclei with DAPI. Scale bar = 25 µm