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Table 3 LINC-PINT (ENSG00000231721) has higher tissue level expression in neuropathologically defined AD cases than in controls

From: Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

Dataset Brain region N BETA (95%CI) p-value
ROSMAP DLPFC 475 0.09 (0.04—0.13) 2.91E-04
Mayo Clinic CER 144 0.36 (0.20—0.52) 1.90E-05
Mayo Clinic TCX 148 0.01 (-0.07—0.10) 7.95E-01
MSBB BM10 124 0.15 (0.01—0.29) 3.26E-02
MSBB BM22 103 0.24 (0.02—0.45) 3.07E-02
MSBB BM36 86 0.20 (0.04—0.37) 1.45E-02
MSBB BM44 106 0.29 (0.10—0.48) 3.03E-03
  1. Differential expression assessed in seven datasets representing six brain regions. ROS = Religious Orders Study, MAP = Memory and Aging Project, MSBB = Mount Sinai Brain bank. CER = Cerebellum, TCX = Temporal Cortex, DLPFC = dorsolateral prefrontal cortex, BM = Brodmann area. se = standard error