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Table 3 LINC-PINT (ENSG00000231721) has higher tissue level expression in neuropathologically defined AD cases than in controls

From: Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

Dataset

Brain region

N

BETA (95%CI)

p-value

ROSMAP

DLPFC

475

0.09 (0.04—0.13)

2.91E-04

Mayo Clinic

CER

144

0.36 (0.20—0.52)

1.90E-05

Mayo Clinic

TCX

148

0.01 (-0.07—0.10)

7.95E-01

MSBB

BM10

124

0.15 (0.01—0.29)

3.26E-02

MSBB

BM22

103

0.24 (0.02—0.45)

3.07E-02

MSBB

BM36

86

0.20 (0.04—0.37)

1.45E-02

MSBB

BM44

106

0.29 (0.10—0.48)

3.03E-03

  1. Differential expression assessed in seven datasets representing six brain regions. ROS = Religious Orders Study, MAP = Memory and Aging Project, MSBB = Mount Sinai Brain bank. CER = Cerebellum, TCX = Temporal Cortex, DLPFC = dorsolateral prefrontal cortex, BM = Brodmann area. se = standard error