Subset | N | N: Sex (%) | N: APOE ε4 dose (%) | Mean age at death (sd) | Mean CAA (sd) | N: Thal (%) | N: Braak stage (%) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Male | Female | 0 | 1 | 2 | 2 | 3 | 4 | 5 | 4 | 5 | 6 | ||||
All | 821 | 370 (45%) | 451 (55%) | 287 (35%) | 414 (50%) | 120 (15%) | 80.1 (8.6) | 0.85 (0.76) | 3 (0%) | 60 (7%) | 69 (8%) | 689 (84%) | 98 (12%) | 280 (34%) | 443 (54%) |
APOEε4 pos (ε4 +) | 534 | 241 (45%) | 293 (55%) | 0 (0%) | 414 (78%) | 120 (22%) | 80.5 (8.2) | 0.96 (0.77) | 1 (0%) | 33 (6%) | 48 (9%) | 452 (85%) | 65 (12%) | 165 (31%) | 304 (57%) |
APOEε4 neg (ε4-) | 287 | 129 (45%) | 158 (55%) | 287 (100%) | 0 (0%) | 0 (0%) | 79.4 (9.2) | 0.72 (0.70) | 2 (1%) | 27 (9%) | 21 (7%) | 237 (83%) | 33 (12%) | 115 (40%) | 139 (48%) |
Males | 370 | 370 (100%) | 0 (0%) | 129 (35%) | 180 (49%) | 61 (16%) | 78.4 (8.1) | 0.98 (0.79) | 1 (0%) | 31 (8%) | 33 (9%) | 305 (82%) | 53 (14%) | 136 (37%) | 181 (49%) |
Females | 451 | 0 (0%) | 451 (100%) | 158 (35%) | 234 (52%) | 59 (13%) | 81.5 (8.7) | 0.79 (0.72) | 2 (0%) | 29 (6%) | 36 (8%) | 384 (85%) | 45 (10%) | 144 (32%) | 262 (58%) |