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Table 1 Characteristics of the dataset

From: Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

Subset N N: Sex (%) N: APOE ε4 dose (%) Mean age at death (sd) Mean CAA (sd) N: Thal (%) N: Braak stage (%)
Male Female 0 1 2 2 3 4 5 4 5 6
All 821 370 (45%) 451 (55%) 287 (35%) 414 (50%) 120 (15%) 80.1 (8.6) 0.85 (0.76) 3
(0%)
60
(7%)
69
(8%)
689
(84%)
98 (12%) 280 (34%) 443 (54%)
APOEε4 pos (ε4 +) 534 241 (45%) 293 (55%) 0 (0%) 414 (78%) 120 (22%) 80.5 (8.2) 0.96 (0.77) 1
(0%)
33
(6%)
48
(9%)
452
(85%)
65 (12%) 165 (31%) 304 (57%)
APOEε4 neg (ε4-) 287 129 (45%) 158 (55%) 287 (100%) 0 (0%) 0 (0%) 79.4 (9.2) 0.72 (0.70) 2
(1%)
27
(9%)
21
(7%)
237
(83%)
33 (12%) 115 (40%) 139 (48%)
Males 370 370 (100%) 0 (0%) 129 (35%) 180 (49%) 61 (16%) 78.4 (8.1) 0.98 (0.79) 1
(0%)
31
(8%)
33
(9%)
305
(82%)
53 (14%) 136 (37%) 181 (49%)
Females 451 0 (0%) 451 (100%) 158 (35%) 234 (52%) 59 (13%) 81.5 (8.7) 0.79 (0.72) 2
(0%)
29
(6%)
36
(8%)
384
(85%)
45 (10%) 144 (32%) 262 (58%)
  1. Characteristics are provided for all AD individuals and each of the subsets defined by APOEe4 carrier status ( ±) and Sex (M/F). N = number, SD = standard deviation, Thal “L” refers to the two Thal phase levels defined as low, Thal “H” refers to the two Thal phase levels defined as high in the converted binary trait