Zika virus induces neuronal and vascular degeneration in developing mouse retina

Table 1 Comparison of the efficacy of SOF and NITD008 against ZIKV-induced retinal pathology

Inhibitor	ZIKV-infected mice with inhibitor	Mice with normal retinas	Inhibition rate (%)
SOF	9	4	44
NITD008	12	12	100

ZIKV was injected into neonatal mice at P0, followed by SOF or NITD008 treatment, and retinas were collected at P14 and compared for abnormalities

ISSN: 2051-5960