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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Zika virus induces neuronal and vascular degeneration in developing mouse retina

Fig. 1

The effects of ZIKV infection on mouse development. a Schematic presentation of our model (generated using BioRender). Neonatal C57BL/6 mice were injected with 20 PFU ZIKV at postnatal day (P) 0 subcutaneously. Eyeballs were collected at P5, P8, P11, P14 and P21. b Graphs represent body weight, body length including tail and head length of control and ZIKV-infected mice at P21. c Representative images of H&E-stained retinal sections from control and ZIKV-infected mice at P21. Graph represents retinal thickness from GCL to ONL. GCL: ganglion cell layer; IPL: inner plexiform layer; INL: inner nuclear layer; OPL: outer plexiform layer; ONL: outer nuclear layer. Scale bar = 50 μm. Data are presented as mean ± S.E.M. n = 7–9 per group. ****p < 0.0001 compared to control mice

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