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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Loss of H3K27 trimethylation is frequent in IDH1-R132H but not in non-canonical IDH1/2 mutated and 1p/19q codeleted oligodendroglioma: a Japanese cohort study

Fig. 5

Histological and immunohistochemical features of IDH1-R132H Mut astrocytoma. The hematoxylin and eosin-stained section demonstrate a low-grade glioma with classic oligodendroglioma morphology 20× (Scale bar = 50 μm) (a) and 40× (Scale bar = 20 μm) (b) magnification. c Positive IDH1-R132H staining. d Retained ATRX staining. e Scattered positive nuclear p53 staining. f Retained H3K27me3 nuclear staining. Chromosome 1p and 19q were confirmed by FISH. Magnification is 20× for cf

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