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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: The degree of astrocyte activation is predictive of the incubation time to prion disease

Fig. 1

nSolver analysis of non-infected samples. (a) Hierarchical clustering of non-infected samples used as control groups showing high regional specificity and reproducibility of the Astorocyte panel. Adult C57Black/6J female (n = 6) and male (n = 3) mice were inoculated i.p. with PBS and analyzed at 197–363 days post-inoculation (Additional file 2: Table S2). (b) Principal component analysis illustrates strong differences in the expression pattern of brain regions (left panel) and no gender-specific differences (right panel). Th, thalamus; HTh, hypothalamus; Ctx, cortex; Hp, hippocampus; F, females; M, males

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