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Table 2 Summary of data from seeding Thy1-G93A Line T3 mice and VLE-G93A

From: Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence

Host Inoculum (Route) # inoculateda #
paralyzed
Age to paralysis or euthanasia
Thy1-G93A PBS 2 0 14.8, 16.6 mo
Thy1-G93A NTg Sp Cord (ISP) 3 0 17.7, 18.2, 19.1 mo
Thy1-G93A Gur G93A Sp Cord (ISP) 4 0 Terminated at 19 mo
Thy1-G93A G37R-L29 Sp Cord (ISP) 4 0 Terminated at 18 mo
VLE-G93A G93A(FVB) Sp Cord (ISP) 8 3 5.3, 8.3, 13.4
VLE-G93A G93A(FVB) Sp Cord (ScN) 11 3 5.8, 8, 10
VLE-G93A PBS (ScN) 5 0 Terminated at 12 mo
  1. aMice that were euthanized for non-MND related conditions, such as fight wounds or tumors, before 12 months of age were excluded, unless otherwise noted