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Table 1 Summary of data for recombinant SOD1 protein seeding experiments

From: Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence

SOD1 protein Avg survival time in yearsa Fibrils visible by EM Induced pathology in
G85R-SOD1:YFP slice culture
bWT N/A Yes Yes
A4V 1.2 ± 0.9 Yes Yes
G37R 18.7 ± 11.4 Yes Yes
G41S 0.9 ± 0.2 No Yes
H46R 17.0 ± 7 Yes Yes
G85R 6.0 ± 4.5 N.D Yes
G93C 13.0 ± 0.4 Yes Yes
E100K 12.0 ± 4.1 Yes Yes
D101N 2.4 ± 0.9 No Yes
  1. aData originally reported in[35]
  2. bInclusive of data originally reported in[17]