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Fig. 8 | Acta Neuropathologica Communications

Fig. 8

From: Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence

Fig. 8

Comparison of the seeding efficiency of L126Z and QV103Z mice in isologous and heterologous seeding. ad Kaplan–Meier survival curves and representative pathology resulting from untagged L126Z SOD1 mice injected with spinal homogenates from paralyzed L126Z or QV103Z mice, and NTg mice. eh Kaplan–Meier survival curves and representative pathology resulting from untagged QV103Z SOD1 mice injected with spinal homogenates from paralyzed L126Z or QV103Z mice, and NTg mice. For each animal 2–3 sections were examined to identify representative images. Paraffin sections of spinal cord from each animal was stained by Campbell-Switzer method as described in Methods. Scale bars = 50 µm

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