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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer’s disease

Fig. 3

Total hippocampus analysis of 3R and 4R tau isoforms show shifts in 4R/3R phenotype over disease course. The total density of 3R and 4R tau containing cells across CA4, CA2/3, CA1, and the subiculum was analyzed across CTE and AD. a Comparative analysis of 3R and 4R tau isoforms within each disease. Paired two-way ANOVAs were used within each disease group to determine altered 3R/4R levels. b Analysis of the 4R/3R tau isoform ratio across each disease. Each dot represents a single case. A one sample T-test was used to determine in each ratio was significantly different than an even ratio value of 1. Dotted line represents a ratio value of 1. *p < 0.05, **p < 0.01, ***p < 0.001

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Acta Neuropathologica Communications

ISSN: 2051-5960

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