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Fig. 10 | Acta Neuropathologica Communications

Fig. 10

From: Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer’s disease

Fig. 10

CA2/3 and CA4 demonstrate the highest ability to discriminate between AD and CTE. To determine which medial temporal lobe structure had the strongest ability to differentiate between severe AD (Braak III-VI) and high CTE (Stage III-IV), a receiver operator characteristic (ROC) curve was used to measure the individual fields across a 4R tau and b 3R tau. The area under curve (AUC) and relevant statistics for their respective regions are listed below the ROC curve. AUC are sorted from highest to lowest. Regions analyzed were CA1, CA2/3, CA4, Subiculum, Temporal cortex grey matter (Temp), and temporal cortex white matter (WM)

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