Fig. 2
From: Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice
Purification of brain-derived Aβ aggregates from transgenic mice. a Schematic of the procedure used to purify PK-resistant Aβ aggregates from the brains of aged TgCRND8 and AppNL−F mice. b Silver-stained SDS-PAGE of the purified Aβ aggregates from TgCRND8 and AppNL−F mice. c Silver-stained urea gels of purified brain-derived and recombinant PK-resistant Aβ aggregates. d Electron micrographs of PK-resistant Aβ aggregates purified from the brains of TgCRND8 and AppNL−F mice. Scale bar = 100 nm (applies to both images)