Fig. 2
From: Design considerations of an IL13Rα2 antibody–drug conjugate for diffuse intrinsic pontine glioma
IL13Rα2 ligand stimulation growth and invasion assay results. Cell models were stimulated with IL13Rα2 ligands to determine effect of IL13Rα2-mediated signaling on cell proliferation and invasion. In a-d, cells were stimulated with recombinant IL-4 and IL-13 at concentrations between 0.5 and 100 ng/mL. In e–g, cells were stimulated with recombinant IL-13 at concentrations at 20 ng/mL, 50 ng/mL, and 100 ng/mL. a SF-8628 stimulated with recombinant human IL-4. b SF-8628 with recombinant human IL-13. c DIPG-24 stimulated with recombinant human IL-4. d DIPG-24 stimulated with recombinant human IL-13. e SF-8628 cellular invasion following IL-13 stimulation. f DIPG-24 cellular invasion following IL-13 stimulation. g CHLA-200 cellular invasion following IL-13 stimulation