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Fig 4. | Acta Neuropathologica Communications

Fig 4.

From: Complement mediates neuroinflammation and cognitive decline at extended chronic time points after traumatic brain injury

Fig 4.

Continuous CR2Crry treatment decreases area of microgliosis in the ipsilateral hemisphere. a 4x stitched immunofluorescence images of Iba-1 (red) microglia/macrophage staining in the three conditions of the study: vehicle, 1-week CR2Crry, and continuous CR2Crry from two different brain coordinates: Bregma − 0.18 mm (+/-0.04) and Bregma − 1.46 mm (+/-0.04). b Quantification of stained images. One-way ANOVA with Bonferroni correction for multiple comparisons. Unpaired T-test: continuous vs. vehicle. Error bars = Mean +/- SEM. *p < 0.05, **p < 0.01, ***p < 0.001. n = 8–11/group.

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