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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy

Fig. 6

GCIs and brainstem neuronal inclusions are differentially reactive to Gallyas silver staining. a Low magnification images of pontine nuclei demonstrate abundant labeling of GCIs, neuritic pathology and neuronal inclusions with 5H12 antibody, b while only a subset of GCIs and rare neuritic pathology are highlighted by Gallyas silver stain. c, d High magnification images of pontine nuclei and e, f inferior olivary nucleus underscore labeling of GCIs, neuritic pathology and neuronal inclusions with 5H12 antibody c, e. Gallyas silver staining only reveals a subset of GCIs and rare neuritic pathology in pontine nuclei and neurons of the inferior olive d, f. Rare neuronal inclusions show faint labeling with Gallyas silver staining (arrowheads, d, f). Asterisks highlight GCIs. Scale bar: 300 μm in a and b, 60 μm in cf

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