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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice

Fig. 2

Reduced Cyp46A1 levels in human sCJD brains. a Demographic details of the post-mortem brain of four different healthy individuals (NBH: normal brain homogenates) and four different sporadic CJD patients (sCJD). b Cyp46A1 levels in the brain homogenates of healthy individuals (NBH) and sCJD patients. β-Actin was used as a loading control and was obtained after stripping of the same membrane. The histogram represents the means ± SEM (n = 4 humans/group) of three independent experiments. Significance = *p < 0.05; Student’s unpaired t test

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