Fig. 5
From: Hsp90 co-chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild-type mice
FKBP52 promotes activation of astrocytes and microglia in aged wild-type mice. Representative images and analysis of hippocampal tissues from 16-month-old wild-type mice expressing AAV9-mCherry, AAV9-Aha1, or AAV9-FKBP52 stained for (a, b) astrocyte marker (GFAP) and (c, d) microglial marker (IBA1). N = 6/AAV. Relative intensity was analyzed by one-way ANOVA followed by Tukey post-hoc test. Statistical significance is indicated by **p < 0.01. Results represented as standard error of the mean (± SEM). Scale bar represents 100 µm; inset scale represents 10 µm