Table 1 Sample characteristics
MCSA (Discovery) | MCSA (Comparison) | ADNI (Replication) | |
|---|---|---|---|
N = 546 | N = 953 | N = 545 | |
Amyloid positive | Amyloid negative | Amyloid positive | |
Age (years) | 77.0 (7.7) | 70.0 (9.7) | 76.1 (7.5) |
Sex | 255 (47%) women | 430 (45%) women | 260 (48%) women |
291 (53%) men | 523 (55%) men | 285 (52%) men | |
Education (years) | 14.6 (2.8) | 14.9 (2.5) | 15.9 (2.8) |
Median visit number | 4 (1.9) | 5 (1.8) | 4 (1.9) |
APOE ɛ4 status | 317 (58%) negative | 756 (79%) negative | 193 (35%) negative |
229 (42%) positive | 197 (21%) positive | 352 (65%) positive | |
Diagnosisa | 458 (85%) CU | 887 (93%) CU | 103 (19%) CU |
78 (14%) MCI | 62 (7%) MCI | 223 (41%) MCI | |
6 (1%) Dementia | 1 (0%) Dementia | 214 (40%) Dementia |