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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Chronically altered NMDAR signaling in epilepsy mediates comorbid depression

Fig. 3

Analysis of the protein changes underlying the observed therapeutic effects in the behavioral assays. a–l For each marker, representative bands from the western blot studies are shown when applicable. Band intensities were corrected based on their corresponding GAPDH expression (a) and the fold change of all markers were calculated compared to the Saline group. The Sham and Saline groups are compared using the Welch’s t-test to determine the changes associated with EAD development and statistical significance is shown as follows: *p < .05. Afterwards, the Saline, NI, Flxc, and Flxc + NI groups are compared using two-way ANOVA to determine the changes brought about by the treatments. Details of the results of this analysis are presented in the main text

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