Fig. 1
From: Chronically altered NMDAR signaling in epilepsy mediates comorbid depression
Validation of EAD development in post-SE rats. a The hippocampal insertion site of the LFP electrode and a sample recording of one of the spontaneous seizures observed 30 days after SE induction. b Comparison of depressive symptoms in the FST between post-SE (Saline) and Sham rats. c & d Comparison of the number of NeuN-immunoreactive (c) and TUNEL-stained (d) cells in 3 subregions of the hippocampus: CA1, CA3, and DG; between post-SE (Saline) and Sham rats. All comparisons were done using the Welch’s t-test and statistical significance is shown as follows: *p < .05, **p < .01