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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Space-occupying brain lesions, trauma-related tau astrogliopathy, and ARTAG: a report of two cases and a literature review

Fig. 7

MAPT (Tau mRNA transcript) expression in astrocytes from human adult brain. Shown are results from three different single-cell and single-nucleus RNAseq studies (from outside laboratories) which analyzed mRNA transcripts in human brain samples. Pie charts (a, c, e, g) show that the proportion of astrocytes that express MAPT was remarkably similar (~ 1/4th of astrocytes evaluated express MAPT transcript) in all three studies. Among the astrocytes that expressed any MAPT (b, d, f), the amount of MAPT transcripts detected in astrocytes was approximately the same as in neurons in the same brains. In AD astrocytes that express MAPT (f), the level of MAPT transcripts detected was higher than in MAPT expressing control astrocytes

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