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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6

Fig. 7

GPC6, a Dlp ortholog exhibits increased expression and altered localization in patient spinal tissues. a Representative image of a control spinal cord (case number CW01-72). N = 7. b Representative image of ALS patient spinal cord. (GWF15-07). N = 16. c Quantification of GPC6 granule number in post-mortem spinal tissue. Arrowheads indicate motor neurons. Significance determined using the Mann U Whitney Test. *Pvalue < 0.05, Scale bar in a 40 μm. Error bars represent SEM

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