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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Cell specific quantitative iron mapping on brain slices by immuno-µPIXE in healthy elderly and Parkinson’s disease

Fig. 7

Quantification of iron in nigrosome 1 neurons in controls (Co) and patients with PD (a). The cellular compartmentation of iron in the SN nigrosome 1 in controls (Co) and patients with PD for different cells types, ferritin positive cells and in the pigment neuromelanin (b). Cellular concentrations of iron were obtained through quantitative element mapping by µPIXE in combination with nickel-enhanced immunocytochemical detection of cell type-specific antigens. Data are given as median values ± SD. n: analyzed cell number; Neurons (Hu C/D), Oligodendrocytes (Olig2), Microglia (IBA-1), Astroglia (GFAP), Ferritin (Fer) and Neuromelanin (NM)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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