Fig. 4

Human α-syn inclusions within the mouse A30P liver co-localize with luminescent conjugated oligothiophenes (LCOs). A–D Human α-syn deposits immunolabeled with the 14H antibody partially co-localize with the p-FTAA and E–H HS-68 LCOs in aged A30P livers. All tissue sections were counterstained with Hoechst (blue). I Individual and J average emission spectra obtained from HS-68-positive human α-syn deposits in the aged A30P liver. K Average emission spectra obtained from HS-68-positive α-syn aggregates from human PD brains (n = 3, blue) and human MSA brains (n = 3, red). Note that the spectra in the human brains were obtained using a filter which cuts off the emitted light at 625 nm in wavelength, which was not used for this study. K Adapted from [37] with permission. © The Author(s). 2019 Open Access. Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/). Bars = 20 µm