Fig. 7
From: Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson’s disease
Reduced CHCHD2 mRNA in erythrocytes predicts PD. a Reduced CHCHD2 mRNA in erythrocytes of PD patients was further confirmed in a larger, validation cohort of 135 normal controls, 73 Early PD, 98 Mid PD and 34 Late PD patients [p < 0.001 each, F (3, 332) = 26.11, one-way ANOVA]. No difference in CHCHD2 mRNA expression was determined among PD groups by Tukey’s multiple comparisons test. b ROC analysis revealed diagnostic values of 80.4% sensitivity and 81.1% specificity of CHCHD2 for PD diagnosis