Fig. 3
From: Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson’s disease
CHCHD2 expression was reduced specifically in the substantia nigra of PD patients when examined by immunohistochemical staining. a Reduced number of CHCHD2 positive cells in substantia nigra of PD patients. Whole slice scanned images of control and PD patients were shown in left and middle panel. Scale bar: 1000 μm. Statistics data of the number of CHCHD2 positive cells was shown in right panel. p < 0.0001, Mann–Whitney U test. b The immunohistochemical staining intensity of CHCHD2 was reduced in substantia nigra of PD patients. p < 0.01, Mann–Whitney U test, n = 3. Scale bar: 50 μm. c CHCHD2 expression was not altered in frontal cortex. p > 0.05, Mann–Whitney U test, n = 3. Scale bar: 50 μm. d CHCHD2 expression was not altered in cerebellum. p > 0.05, Mann–Whitney U test, n = 3. Scale bar: 50 μm