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Table 3 LFB ratings of WM degeneration in core regions in FTLD-Tau vs. FTLD-TDP

From: Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology

 

FTLD-Tau

FTLD-TDP

P value#

ACG

1 (1–2) N = 36

1 (0–2) N = 51

0.048

ANG

1 (0–1) N = 34

1 (0–1) N = 50

0.435

MFC

1 (1–3) N = 38

0 (0–2) N = 58

0.003

OFC

1 (0–3) N = 33

1 (0–2) N = 55

0.964

STG

1 (1–1) N = 34

1 (1–3) N = 48

0.282

  1. Values depict median (interquartile range) of ordinal scores
  2. ACG = anterior cingulate gyrus; ANG = angular gyrus; FTLD-Tau = frontotemporal lobar degeneration with inclusions of the tau protein; FTLD-TDP = frontotemporal lobar degeneration with inclusions of the TDP-43 protein; LFB = luxol fast blue; MFC = middle frontal cortex; OFC = orbitofrontal cortex; STG = superior temporal gyrus; WM = white matter
  3. #LFB ordinal ratings were compared between pathology groups using Mann Whitney U analysis
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Acta Neuropathologica Communications

ISSN: 2051-5960

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