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Table 3 LFB ratings of WM degeneration in core regions in FTLD-Tau vs. FTLD-TDP

From: Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology

  FTLD-Tau FTLD-TDP value#
ACG 1 (1–2) N = 36 1 (0–2) N = 51 0.048
ANG 1 (0–1) N = 34 1 (0–1) N = 50 0.435
MFC 1 (1–3) N = 38 0 (0–2) N = 58 0.003
OFC 1 (0–3) N = 33 1 (0–2) N = 55 0.964
STG 1 (1–1) N = 34 1 (1–3) N = 48 0.282
  1. Values depict median (interquartile range) of ordinal scores
  2. ACG = anterior cingulate gyrus; ANG = angular gyrus; FTLD-Tau = frontotemporal lobar degeneration with inclusions of the tau protein; FTLD-TDP = frontotemporal lobar degeneration with inclusions of the TDP-43 protein; LFB = luxol fast blue; MFC = middle frontal cortex; OFC = orbitofrontal cortex; STG = superior temporal gyrus; WM = white matter
  3. #LFB ordinal ratings were compared between pathology groups using Mann Whitney U analysis