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Table 5 Correlations between p-tau Thr181 levels and behavioral parameters in the light dark escape task

From: Laterality and region-specific tau phosphorylation correlate with PTSD-related behavioral traits in rats exposed to repetitive low-level blast

Light dark escape

p-tau (Thr181)

Pearson

Kendall's tau-b

Spearman's rho

Correlation coefficient

p value

Correlation coefficient

p value

Correlation coefficient

p value

Left anterior cortex

Total time light side

 − .526

.119

 − .511

.040

 − .673

.033

Total distance light side

 − ..545

.103

 − .556

.025

 − .745

.013

Right anterior cortex

Total time light side

 − .474

.166

 − .333

.180

 − .467

.174

Total distance light side

 − .544

.104

 − .467

.060

 − .612

.060

Left Hippocampus

Total time light side

 − .447

.195

 − .333

.180

 − .430

.214

Total distance light side

 − .287

.421

 − .200

.421

 − .212

.556

Right Hippocampus

Total time light side

 − .633

.050

 − .556

.025

 − .648

.043

Total distance light side

 − .700

.024

 − .600

.016

 − .770

.009

Left Amygdala

Total time light side

 − .024

.947

 − .022

.929

 − .091

.803

Total distance light side

.219

.543

.022

.929

 − .018

.960

Right Amygdala

Total time light side

 − .026

.944

 − .067

.788

 − .139

.701

Total distance light side

.144

.691

.067

.788

 − .018

.960

Left Posterior Cortex

Total time light side

.281

.432

.156

.531

.321

.365

Total distance light side

.067

.853

.111

.655

.176

.627

Right Posterior Cortex

Total time light side

.237

.510

.111

.655

.164

.651

Total distance light side

.406

.244

.156

.531

.212

.556

  1. P-tau Thr181 were measured for the same rats studied in Table 3 at 40 weeks after blast exposure [21] and correlated with total time on the light side or total distance moved on the light side in a light dark escape task tested at 29 weeks after blast exposure [80]. Five blast and five control animals were analyzed. Correlations with p values equal to or less than 0.05 are indicated in bold
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Acta Neuropathologica Communications

ISSN: 2051-5960

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