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Table 12 Correlations between p-tau Thr181 and total tau levels with the discrimination index in a novel object localization task

From: Laterality and region-specific tau phosphorylation correlate with PTSD-related behavioral traits in rats exposed to repetitive low-level blast

Novel object localization (discrimination index)
p-tau (Thr181) Pearson Kendall's tau-b Spearman's rho
Correlation coefficient p value Correlation coefficient p value Correlation coefficient p value
Left anterior cortex  − .791 .006  − .644 .009  − .842 .002
Right anterior cortex  − .781 .008  − .556 .025  − .685 .029
Left Hippocampus  − .299 .402  − .111 .655  − .200 .580
Right Hippocampus  − .732 .016  − .600 .016  − .794 .006
Left Amygdala .110 .762  − .067 .788  − .030 .934
Right Amygdala  − .377 .283  − .111 .655  − .273 .446
Left Posterior Cortex .136 .707 .022 .929 .055 .881
Right Posterior Cortex  − .238 .509  − .111 .655  − .127 .726
Total tau vs. discrimination index
Left anterior cortex .142 .696  − .022 .929 .055 .881
Right anterior cortex  − .367 .296 .200 .421  − .285 .425
Left Hippocampus .562 .091 .467 .060 .648 .043
Right Hippocampus .409 .240 .422 .089 .527 .117
Left Amygdala  − .142 .695  − .111 .655  − .111  − .067
Right Amygdala .462 .179 .378 .128 .515 .128
Left Posterior Cortex .151 .677 .111 .655 .127 .726
Right Posterior Cortex  − .704 .023  − .467 .060  − .673 .033
  1. P-tau Thr181 levels were previously determined by Western blotting with the antibody AT270 at 40 weeks after blast exposure. [21]. P-tau levels were correlated with the discrimination index in a novel object localization task previously found to be affected in the same blast-exposed rats at 33 weeks following blast exposure [80]. Five blast and five control animals were analyzed. Correlations with p values less than 0.05 are indicated in bold