Fig. 1
From: Iron loading is a prominent feature of activated microglia in Alzheimer’s disease patients
Increased iron-positive and corresponding FTL+-microglia in Alzheimer’s disease a MTG cortex of Alzheimer patients shows increased positivity for iron inside cells with microglial morphology. b Significant increase of iron-positive cells in Alzheimer patients (n = 11) compared to controls (n = 9)(Mean, Student’s t-test). c Iron-positive microglia number only increased in cases with severe signal alterations on iron-sensitive T2*-w MRI, reflected by MRI severity score. d FTL expression reflects intracellular iron accumulation. Scale overview images, 200 μm. Scale zooms, 30 μm