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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Nucleolar stress in C9orf72 and sporadic ALS spinal motor neurons precedes TDP-43 mislocalization

Fig. 4

Nucleolar size reduction occurs in neurons with and without TDP-43 mislocalization. a–f Nucleolar area (a, b), nuclear area (c, d) and cytoplasmic area (e, f) are decreased in C9-ALS with or without TDP-43 mislocalization and in SALS neurons compared to controls. g–i Scatterplots of group average (top) and individual neurons (bottom) comparing nucleolar and nuclear area (g), nucleolar and cytoplasmic area (h) and nuclear and cytoplasmic area (i) (lines indicate linear regression)

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