Fig. 1
From: Nucleolar stress in C9orf72 and sporadic ALS spinal motor neurons precedes TDP-43 mislocalization
Nucleolar shrinkage occurs in C9-ALS and SALS spinal motor neurons. a Nucleolar area is identified by fibrillarin staining (green), nuclear area is identified by DAPI and cytoplasmic area is identified by autofluorescence in control, C9-ALS and SALS spinal motor neurons. b–g Average nucleolar (b, c), nuclear (d, e) and cytoplasmic area (f, g) were decreased in C9-ALS and SALS cases compared to controls