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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation

Fig. 5

a. A set of 25 top most-confident genes differentially overexpressed in CNS_NBL (blue top line) and GBM_MID (pink top line) respectively allows one to discriminate clearly between these tumor cohorts with ANKRD55 on the top genes for CNS_NBL (Row Z-Scores: green: from 0 to − 6; red: from 0 to 6). b. ANKRD55 expression levels were significantly higher in CNS_NBL (blue boxplots) in comparison to other molecular groups. c. Intense ANKRD55 immunostaining was found in CNS_NBL but GBM_MID were negative (The scale bars: 50 μm)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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