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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier – phenotypic variability in autosomal dominant Alzheimer’s disease

Fig. 2

Representative images of 4G8-stained sections of mid-frontal cortex (a), superior temporal gyrus (b), visual cortex (c), cingulate gyrus (d), amygdala (e) and cerebellum (f) reveal widespread parenchymal and vascular (inserts) Aβ-pathology throughout the neuroaxis. Cerebral amyloid angiopathy was more prominent in cortical and leptomeningeal vasculature with no substantial involvement of cortical capillaries. Overview images (scale bar = 1000 μm) and high magnification insert (scale bar = 50 μm)

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