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Table 1 Demographic and clinical characteristic of patients with PSP, and pathology-controls

From: Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity

 

PSP (n = 31)

PSP-RS (n = 22)

Variant PSP (n = 9)

Controls (n = 6)

p-value Control – PSP

Age (years) at Death

 Mean ± SD

75.4 ± 7.4

73.2 ± 7.1

80.7 ± 5.1

70 ± 5.6

n.s.a

  (Range)

(63–90)

(63–90)

(73–90)

(62–77)

 

Number (%) of males

19 (61%)

14 (63%)

5 (56%)

2 (33%)

n.s.b

Age (years) at symptom onset

 Mean ± SD

71.5 ± 8.3

66.0 ± 8.2

73.7 ± 5.5

–

–

  (Range)

(51–86)

(51–86)

(68–86)

  

Disease duration (years)

 Mean ± SD

6.9 ± 2.9

7.0 ± 2.8

6.9 ± 3.3

–

–

 Range

(3.1–15.5)

(4.2–15.5)

(3.1–14.3)

  

Brain weight (g)

 Mean ± SD

1196 ± 142.7

1193 ± 151.5

1209 ± 117.7

1222 ± 47.8

n.s.a

 Range

(960–1500)

(960–1500)

(1079–1400)

(1153–1263)

 
  1. PSP progressive supranuclear palsy, SD standard deviation, n.s. not significant, p > 0.05 uncorrected, by a Student’s t-test or b Fischer’s exact test, Subscript to t is degrees of freedom