From: Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity
 | PSP (n = 31) | PSP-RS (n = 22) | Variant PSP (n = 9) | Controls (n = 6) | p-value Control – PSP |
---|---|---|---|---|---|
Age (years) at Death | |||||
 Mean ± SD | 75.4 ± 7.4 | 73.2 ± 7.1 | 80.7 ± 5.1 | 70 ± 5.6 | n.s.a |
  (Range) | (63–90) | (63–90) | (73–90) | (62–77) |  |
Number (%) of males | 19 (61%) | 14 (63%) | 5 (56%) | 2 (33%) | n.s.b |
Age (years) at symptom onset | |||||
 Mean ± SD | 71.5 ± 8.3 | 66.0 ± 8.2 | 73.7 ± 5.5 | – | – |
  (Range) | (51–86) | (51–86) | (68–86) |  |  |
Disease duration (years) | |||||
 Mean ± SD | 6.9 ± 2.9 | 7.0 ± 2.8 | 6.9 ± 3.3 | – | – |
 Range | (3.1–15.5) | (4.2–15.5) | (3.1–14.3) |  |  |
Brain weight (g) | |||||
 Mean ± SD | 1196 ± 142.7 | 1193 ± 151.5 | 1209 ± 117.7 | 1222 ± 47.8 | n.s.a |
 Range | (960–1500) | (960–1500) | (1079–1400) | (1153–1263) |  |