Fig. 1
From: Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity
Representative images of locus coeruleus in control and PSP cases. a Photographs of pons sections including the locus coeruleus (arrows). b Micrographs showing the location of locus coeruleus near the floor of the 4th ventricle in a control and PSP case (red arrows). Stitched images from micrographs taken using a 4X objective. c Micrographs taken using a 20X objective, red arrows indicate representative examples of pigmented neurons of the locus coeruleus and hollow red arrows indicate examples of pigmented neurons with tau-inclusions. b and c Sections were stained for hyperphosphorylated tau (AT8) in purple using methyl green as counterstain, endogenous neuromelanin shown in brown